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5 or 1 milligram of tesofensine was double that of weight loss seen with the currently available diet drugs Acomplia (rimonabant) or Meridia (sibutramine), the researchers said. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Rimonabant, brand named Acomplia, is an anti-obesity drug that may help treat addiction, the team noted. Rimonabant is not yet approved for use in the United States, where it is known as Zimulti. 25 percent increase in percent atheroma volume (PAV) in those taking rimonabant, compared to 0. The undeclared active pharmaceutical ingredients in some of these products include sibutramine (a controlled substance), rimonabant ( a drug not approved for marketing in the United States), phenytoin ( an anti-seizure medication), and phenolphthalein (a solution used in chemical experiments and a suspected cancer causing agent).
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